April 15, 2022  — Centene Corporation’s (NYSE: CNC) Board of Directors issued the following statement on April 15 2022:

The Centene Board has accepted the resignation of Leslie V. Norwalk, Esq. as a member of the Board. The Board appreciates Leslie’s contribution to the Company and her service.

The Board remains committed to the continued strengthening of the Company’s corporate governance practices. Since November 2021, the company has implemented significant governance enhancements, including the appointment of five new Board members, refreshed Chairs of the Nominating and Governance, Audit, and Compensation Committees, the separation of the roles of CEO and Chairman, the appointment of a new lead independent director, and the implementation of a mandatory Board retirement age.

The entire Board is united in its support for the Company’s new CEO, Sarah London, and her highly experienced, effective leadership team, all of whom are focused on executing the Company’s value creation strategy.

Information from SEC filing:

On April 11, 2022, Leslie Norwalk resigned, effective immediately, as a member of the board of the directors (the “Board”) of Centene Corporation (the “Company”).
Consistent with Ms. Norwalk’s resignation letter, which is filed herewith as Exhibit 17.1, the Company believes that Ms. Norwalk resigned because of her disagreement with
Board governance process and Board and committee leadership.

At the time of her resignation, Ms. Norwalk served on the Board’s Compliance Committee, Environmental and Social Responsibility Committee and Government and
Regulatory Affairs Committee.

As part of its ongoing commitment to strengthening the Company’s corporate governance practices, since November 2021 the Company has implemented significant
governance enhancements, including appointment of five new Board members, refreshment of Chairs of the Nominating and Governance, Audit, and Compensation
Committees, separation of the roles of CEO and Chairman, the appointment of a new lead independent director, and the implementation of a mandatory Board retirement age.
In addition, the entire Board is united in its support for the Company’s new CEO, Sarah London, and her highly experienced, effective leadership team, all of whom are focused
on executing the Company’s value creation strategy.

The Company provided Ms. Norwalk with a copy of the disclosures contained in this Current Report no later than the date on which this Current Report is being filed with the
Securities and Exchange Commission. The Company also provided Ms. Norwalk with the opportunity to furnish the Company with a letter stating whether she agrees or
disagrees with the statements made in this Current Report and the respects in which she disagrees.

Centene Corporation, a Fortune 25 company, is a leading healthcare enterprise that is committed to helping people live healthier lives. The Company takes a local approach – with local brands and local teams – to provide fully integrated, high-quality, and cost-effective services to government-sponsored and commercial healthcare programs, focusing on under-insured and uninsured individuals. Centene offers affordable and high-quality products to nearly 1 in 15 individuals across the nation, including Medicaid and Medicare members (including Medicare Prescription Drug Plans) as well as individuals and families served by the Health Insurance Marketplace, the TRICARE program, and individuals in correctional facilities. The Company also serves several international markets, and contracts with other healthcare and commercial organizations to provide a variety of specialty services focused on treating the whole person. Centene focuses on long-term growth and value creation as well as the development of its people, systems, and capabilities so that it can better serve its members, providers, local communities, and government partners.

Centene uses its investor relations website to publish important information about the Company, including information that may be deemed material to investors. Financial and other information about Centene is routinely posted and is accessible on Centene’s investor relations website, https://investors.centene.com/.