His work has shaped national and international standards of care for head and neck cancers.
April 1, 2026 — Tampa General Hospital (TGH) has appointed internationally recognized medical oncologist and clinical researcher Dr. Marshall Posner as associate director of Clinical Investigations at the TGH Cancer Institute.
Posner is a world-class leader in the field of medical oncology, a gifted physician and a highly accomplished clinical researcher with over 280 peer-reviewed publications, including top-tier journals such as the New England Journal of Medicine, Nature Communications, Science, the Journal of Clinical Investigations, the Journal of Clinical Oncology, Cancer Research, the Proceedings of the National Academy of Sciences (PNAS) and the Journal of Virology, among others.
He graduated from Yale University, New Haven, Connecticut and Tufts University School of Medicine, Boston. He completed his residency in internal medicine at Boston City Hospital and a fellowship in medical oncology at the Dana-Farber Cancer Institute, Boston where he earned the position of medical director of the head and neck oncology program, and associate professor at Harvard Medical School, Boston.
In 2010, Posner was recruited to the Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai in New York City as professor of Medicine, medical director, Head and Neck Cancer Program, and associate director, Cancer Clinical Trials Office. During his tenure at the Mount Sinai Health System, he also served as associate director of the Center for Personalized Cancer Therapeutics, associate director for Research Infrastructure and co-leader of the Cancer Clinical Investigation Program, National Cancer Institute Cancer Center Support Grant (P30 Grant) and co-chair, of the Protocol Review and Monitoring Committee (PRMC). He is board-certified in Internal Medicine and Medical Oncology.
Posner will continue to serve in his current role as the medical director of the Cancer Center Clinical Research Trial Office and head and neck oncologist at the Cancer Center of South Florida in Palm Beach Gardens, expanding collaboration between the two organizations. “Dr. Posner is a transformative addition to our team,” said Dr. Eduardo M. Sotomayor, vice president and executive director of the TGH Cancer Institute. “His expertise in clinical trials design and innovation, together with his ample knowledge of immunology and viral oncology, will elevate our clinical research enterprise and accelerate our ability to bring groundbreaking therapies to patients. We are also excited about his leadership within our microbial oncology program that will position Tampa General at the forefront of human-papillomaviruses (HPV)‑related cancer research.”
In his new role, Posner will collaborate closely with Tampa General and USF Health Morsani College of Medicine researchers to expand investigator‑initiated trials, pharma-sponsored and National Cancer Institute-sponsored clinical trials, strengthen translational pipelines and integrate microbial and immunologic science into new therapeutic strategies.
“Dr. Posner’s work marks a major milestone in our mission to deliver world‑class cancer care supported by groundbreaking research,” said Dr. Abraham Schwarzberg, executive vice president, chief president of Tampa General Provider Network and co‑vice president of Clinical and Translational Research, TGH | USF Health Joint Office of Clinical Research. “His leadership will help us grow a robust clinical research infrastructure and accelerate discovery for patients across the state of Florida and beyond.”
“Tampa General’s commitment to innovation, collaboration and patient‑centered care creates an ideal environment for advancing microbial oncology and developing new treatments for HPV‑related cancers,” Posner said. “I look forward to working with this exceptional team while continuing my clinical and research efforts at the Cancer Center of South Florida.”
The TGH Cancer Institute continues to grow as a statewide leader in cancer care, offering patients access to advanced therapies, multidisciplinary expertise and a rapidly expanding portfolio of clinical trials.
The TGH Cancer Institute — among Florida’s few cancer centers backed by academic medicine through its partnership with the USF Health Morsani College of Medicine — ranks among the nation’s top 10% of hospitals in U.S. News & World Report’s Best Hospitals 2025-2026. The Florida Department of Health has recognized the TGH Cancer Institute in partnership with the USF Health Morsani College of Medicine as a Cancer Center of Excellence. It holds accreditations from the American College of Surgeons Commission on Cancer, the American Society of Clinical Oncology’s Quality Oncology Practice Initiative and the Foundation for the Accreditation of Cellular Therapy for excellence in stem cell and cellular therapy. The institute is a member of the Association of American Cancer Institutes, recognized for leadership in research, treatment, education and outreach and was named among Newsweek’s America’s Best Cancer Hospitals. For more information on the TGH Cancer Institute, visit TGH Cancer Institute | Comprehensive Cancer Care in Tampa.
ABOUT TAMPA GENERAL HOSPITAL
Tampa General Hospital, the Tampa Bay region’s only academic health system, is a 1,530-bed not-for-profit network of hospital and outpatient services spanning across Florida. As the only center for Level l trauma and comprehensive burn care center serving 23 counties, Tampa General delivers world-class care. The system’s hospitals include Tampa General Hospital, Tampa General Rehabilitation Hospital, Tampa General Behavioral Health Hospital, all in Tampa; Tampa General Brooksville, Tampa General Spring Hill and Tampa General Crystal River. Tampa General is the highest-ranked hospital in Tampa Bay in U.S. News & World Report’s 2025-2026 Best Hospitals, with six medical specialties ranking among the top 50 in the nation and five additional medical specialties ranked among the top 10% best hospital programs in the United States. As the first hospital in Florida to open a clinical command center for real-time situational awareness, the academic health system has elevated its digital care coordination center to the next level by leveraging artificial intelligence (AI) and its analytics platform across inpatient and outpatient care to ensure patients receive leading-edge care as quickly and safely as possible. Tampa General’s commitment to growing and developing its team members is recognized by three prestigious Forbes magazine rankings — in the 2026 America’s Best Large Employers ranked as the Tampa Bay region’s #1 employer in the health care category for the sixth year in a row, and among the top five in the state of Florida, in the 2025 Best Employers by State and the 2023 America’s Best Employers for Women.
Tampa General is the area’s safety-net hospital, caring for anyone regardless of ability to pay; in fiscal year 2024, Tampa General provided a net community benefit of approximately $289.1 million in the form of health care for underinsured patients, community education and financial support to community health organizations in Tampa Bay. It is recognized as one of the adult solid organ transplant centers in the nation and is the primary teaching hospital for the USF Health Morsani College of Medicine. With five medical helicopters, Tampa General transports critically injured or ill patients from surrounding counties to receive the advanced care their conditions require. Tampa General has a nationally accredited comprehensive stroke center and its 32-bed Neuroscience Intensive Care Unit is the largest on the West Coast of Florida. It is home to the Muma Children’s Hospital at TGH, the Jennifer Leigh Muma 82-bed neonatal intensive care unit and a nationally accredited rehabilitation center. Tampa General’s footprint includes TGH North, which consists of three hospitals and several outpatient locations in Citrus and Hernando counties; 17 Tampa General Medical Group Primary Care offices; TGH Family Care Center Kennedy; two TGH outpatient centers; TGH Virtual Health; and 20 TGH Imaging outpatient radiology centers throughout Hillsborough, Pasco, Pinellas and Palm Beach counties. Tampa Bay area residents receive world-class care from the TGH Urgent Care, powered by the Fast Track network of clinics. To see a medical care professional live anytime, anywhere on a smartphone, tablet or computer, visit Virtual Health | Tampa General Hospital (tgh.org). For more information, go to www.tgh.org.