James Dallas Appointed Acting Chairman of the Board of Directors~

Company to be led on interim basis by expanded Office of the Chairman: Sarah London, Brent Layton, Drew Asher and Shannon Bagley~

February 24, 2022  — Centene Corporation (NYSE: CNC) (“Centene”) announced today that its Board of Directors approved a request from Michael Neidorff, Chairman & Chief Executive Officer, for a medical leave of absence. James Dallas has been named Acting Chairman of the Board.

Effective immediately, day-to-day management of the Company will be led on an interim basis by an expanded Office of the Chairman, consisting of Sarah London, Vice Chairman of the Board; Brent Layton, President and Chief Operating Officer; Drew Asher, Chief Financial Officer; and Shannon Bagley, Chief Administrative Officer.

The Office of the Chairman will report to James Dallas in his position as Acting Chairman of the Board.

“I have full faith and confidence in this leadership team and their ability to execute on Centene’s Value Creation strategy,” said Neidorff. “As I deal with a treatable medical condition, I want to thank the team for their ongoing work and dedication to lead this exceptional company.”

Neidorff started at Centene in 1996 when it was a single health plan. He led the company for 26 years and oversaw the company’s growth to a Fortune 24 enterprise with revenues of over $125 billion.

As previously announced, the Board of Directors is engaged in a thorough selection process to appoint a new CEO, currently targeted for completion no later than Q2 2022.

About Centene Corporation

Centene Corporation, a Fortune 25 company, is a leading multi-national healthcare enterprise that is committed to helping people live healthier lives. The Company takes a local approach – with local brands and local teams – to provide fully integrated, high-quality, and cost-effective services to government-sponsored and commercial healthcare programs, focusing on under-insured and uninsured individuals. Centene offers affordable and high-quality products to nearly 1 in 15 individuals across the nation, including Medicaid and Medicare members (including Medicare Prescription Drug Plans) as well as individuals and families served by the Health Insurance Marketplace, the TRICARE program, and individuals in correctional facilities. The Company also serves several international markets, and contracts with other healthcare and commercial organizations to provide a variety of specialty services focused on treating the whole person. Centene focuses on long-term growth and value creation as well as the development of its people, systems, and capabilities so that it can better serve its members, providers, local communities, and government partners.

Centene uses its investor relations website to publish important information about the Company, including information that may be deemed material to investors. Financial and other information about Centene is routinely posted and is accessible on Centene’s investor relations website, https://investors.centene.com/.