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By Elliot Pearson, MD

If you’ve been listening to the news, you’ve probably heard people talking about a condition called myocarditis. Myocarditis is defined as inflammation of the heart muscle, and it can result from a viral infection, immune-mediated disease, or immunomodulatory treatments. There can be a wide range at presentation, but symptoms generally include chest pain, difficulty breathing, and/or palpitations. Mild presentations of myocarditis can resolve with minimal to no treatment. Severe myocarditis can reduce the heart’s ability to pump, elicit abnormal rhythms of the heart (arrhythmias), and result in permanent damage.

This condition has been reported to affect the heart in adolescent boys after Covid-19 vaccination. Clinical trials of the COVID-19 vaccines lacked sufficient power to detect this rare complication. Now that more than 6 billion doses of the vaccine have been administered worldwide, cases of myocarditis following COVID-19 vaccination have been reported. This rare side effect has sparked a lot of media attention, resulting in many rumors on social media and beyond. Research coordinated by the medical community has provided answers to these questions.

Notably, a large case series out of England, including more than 38 million adults ages 16 and older, has studied the incidence of myocarditis in patients after COVID-19 vaccine or infection. This is the largest study to date of cardiac outcomes after COVID-19 vaccination or infection, and the findings are published in the December 2021 issue of Nature Medicine.

Fortunately, post-vaccine myocarditis remains rare, with occurrence ranging between one and ten for every million patients, depending upon the type of vaccine and patient demographic. Post-vaccine myocarditis was more likely to be seen in patients younger than 40 years. It was also more likely to occur after receiving an mRNA vaccine, and most occurred within the first week after vaccination. However, the myocarditis was typically mild, with symptoms resolving in a short time frame and with minimal treatment.

The study also reports on the incidence of myocarditis after testing positive for COVID-19. Importantly, patients were at least 4x more likely to have myocarditis from COVID-19 infection than from the vaccine. Also, heart disease from COVID-19 infection is more severe and may require a longer hospitalization or more involved treatment. In addition, the study observed an increased risk of pericarditis and cardiac arrhythmias for those who tested positive for COVID-19 infection.

Researchers and physicians generally agree that the vaccine is a safer option, when compared to the cardiac risks of getting the COVID-19 infection itself. Nowadays, there is a lot of misinformation which can be misleading or confusing. When it comes to making an important decision about your health, be sure to talk to your own doctor about any questions or concerns you may have. They should be able to answer most questions about the vaccine and help you determine which option is best for you.

Dr. Elliot Pearson is a Pediatric Cardiologist at KIDZ Medical in Palm Beach County.

Pull-Out Quote:

Findings reported in Nature Medicine:

• Post-vaccine myocarditis remains rare, occurring between one and ten times for every million patients.

• Post-vaccine myocarditis is more likely to occur in patients younger than 40.

• Myocarditis is more likely to occur after an mRNA vaccine.

• Patients were at least 4x more likely to have myocarditis from COVID-19 infection than from the vaccine.

• Heart disease from COVID-19 infection is more severe and may require a longer hospitalization or more involved treatment.