July 20, 2020 – Cleveland Clinic’s Weston hospital announced today a new clinical trial aimed at helping COVID-19-positive patients who show signs of severe pneumonia and hyperinflammation due to the illness. This clinical trial is an in-patient study that will explore the use of the drug Mavrilimumab to reduce the progression of acute respiratory failure and need for ventilation in patients.   
 
The multi-center clinical trial is being conducted in collaboration with Cleveland Clinic in Ohio.  Participants must be 18 or older and meet certain criteria, including a positive test result, hospital admission due to COVID-19 and onset of symptoms beginning no longer than 14 days from beginning of treatment. Participants will be monitored for a 28-day period. This clinical trial is currently underway at the Weston hospital. 
 
“At Cleveland Clinic Florida, we are committed to finding innovative therapies and treatments for patients in our community and across our country,” said Dr. Joseph Iannotti, Interim CEO and President of Cleveland Clinic Florida. “We are hopeful that this clinical trial will allow us to reduce the complications associated with SARS-Cov-2 and help create additional care options to combat the virus.” 
 
Since early April, Cleveland Clinic Florida has been researching treatment options for COVID-19, and is currently conducting trials for convalescent plasma, the use of Vitamin C and Zinc, and Canakinumab. 
 
Cleveland Clinic Florida continues to work closely with Cleveland Clinic Ohio to lead the way in innovative research for COVID-19 patients. Most recently, the Cleveland Clinic Florida Research and Innovations Center opened in Port St. Lucie, Florida which will be an essential part of research for SARS-Cov-2. The research facility is integral to the work done by the Cleveland Clinic Center for Global and Emerging Pathogens Research, a global initiative that launched in late April, and will work to develop and advance therapies and the prevention of infectious diseases in humans, including COVID-19 and cancers. 
For more information about Cleveland Clinic Florida, please visit www.ccf.org. 
 
About the Cleveland Clinic Florida Region
The Cleveland Clinic Florida region is a nonprofit, multi-specialty healthcare provider that integrates clinical and hospital care with research and education. The Florida region now includes Cleveland Clinic Indian River Hospital, Cleveland Clinic Martin Health, and Cleveland Clinic Weston Hospital, with five hospitals and numerous outpatient centers in Broward, Palm Beach, Martin, St. Lucie and Indian River Counties. The Florida region is an integral part of Cleveland Clinic in Ohio, where providing outstanding patient care is based upon the principles of cooperation, compassion and innovation. Physicians at Cleveland Clinic are experts in the treatment of complex conditions that are difficult to diagnose. For more information about Cleveland Clinic Florida, visit www.clevelandclinicflorida.org. Follow us on Twitter and Facebook.